Article
The rainbow trout CMP-sialic acid synthetase utilises a nuclear localization signal different from that identified in the mouse enzyme.
Glycobiology - 1 Sept 2007
Tiralongo Joe, Fujita Akiko, Sato Chihiro, Kitajima Ken, Lehmann Friederike, Oschlies Melanie, Gerardy-Schahn Rita, Münster-Kühnel Anja K
Abstract excerpt
The terminal sugar sialic acid (Sia) plays a pivotal role in cell-cell interaction and recognition. A prerequisite for the biosynthesis of sialoglycoconjugates is the activation of Sia to cytidine monophosphate-Sia (CMP-Sia), by CMP-Sia synthetases (CMP-Sia-syn). CMP-Sia-syn are conserved from ba...
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