Article
Relationship between VNTR polymorphisms of the human dopamine transporter gene and expression in post-mortem midbrain tissue.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2007
Brookes Keeley J, Neale Benjamin M, Sugden Karen, Khan Nadeem, Asherson Philip, D'Souza Ursula M
Abstract excerpt
Attention deficit hyperactivity disorder (ADHD) is currently one of the most prevalent childhood behavioral disorders. The disorder is found to be highly heritable, suggesting a large genetic component. Association studies have repeatedly implicated the dopamine transporter (DAT1) gene, and in particular the 10-repeat allele of a variable number tandem repeat (VNTR) polymorphism located in the 3'UTR of the gene....
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