Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y).

The Journal of clinical endocrinology and metabolism - 1 Sept 2007

Swanson Charlotte, Lorentzon Mattias, Vandenput Liesbeth, Labrie Fernand, Rane Anders, Jakobsson Jenny, Chouinard Sarah, Bélanger Alain, Ohlsson Claes

Abstract excerpt

CONTEXT: Sex steroids are involved in the regulation of pubertal cortical bone expansion in males. In vitro studies have indicated that the enzyme uridine diphosphate glucuronosyltransferase (UGT) 2B7 has the capacity to glucuronidate sex steroids and their metabolites. OBJECTIVE: Our objective was to determine the impact of the H(268)Y polymorphism in the UGT2B7 gene on interindividual variation of serum levels...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Bone and Bones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronosyltransferase

Share to Gonadal Steroid Hormones

Share to Histidine

Share to Models, Biological

Share to Organ Size

Share to Tyrosine

Source

Identifiers

PMID: 17579197
DOI: 10.1210/jc.2007-0530

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y).PMID 17579197Read ↗

Polymorphisms in the aromatase gene predict areal BMD as a result of affected cortical bone size: the GOOD study.Semantic proximity Read ↗

A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys.Semantic proximity Read ↗

Genome-wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density.Semantic proximity Read ↗

UGT2B17 gene deletion associated with an increase in bone mineral density similar to the effect of hormone replacement in postmenopausal women.Semantic proximity Read ↗

Perturbed sex steroid status in men with idiopathic osteoporosis and their sons.Semantic proximity Read ↗

A common promotor variant in the cytochrome P450c17alpha (CYP17) gene is associated with bioavailability testosterone levels and bone size in men.Semantic proximity Read ↗

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.Semantic proximity Read ↗

Normalized Testosterone Glucuronide as a Potential Urinary Biomarker for Highly Variable UGT2B17 in Children 7-18 Years.Semantic proximity Read ↗

Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk.Semantic proximity Read ↗

Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women.Semantic proximity Read ↗

Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism.Semantic proximity Read ↗

Effect of Environmental Factors and Gender on the Heritability of Bone Mineral Density and Bone SizeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.