Article
Mapping of chimpanzee full-length cDNAs onto the human genome unveils large potential divergence of the transcriptome.
Gene - 1 Sept 2007
Sakate Ryuichi, Suto Yumiko, Imanishi Tadashi, Tanoue Tetsuya, Hida Munetomo, Hayasaka Ikuo, Kusuda Jun, Gojobori Takashi, Hashimoto Katsuyuki, Hirai Momoki
Abstract excerpt
The genetic basis of the phenotypic difference between human and chimpanzee is one of the most actively pursued issues in current genomics. Although the genomic divergence between the two species has been described, the transcriptomic divergence has not been well documented. Thus, we newly sequenced and analyzed chimpanzee full-length cDNAs (FLcDNAs) representing 87 protein-coding genes. The number of nucleotide...
Topics
- 3' Untranslated Regions
- 5' Untranslated Regions
- Alu Elements
- Animals
- Chromosome Mapping
- DNA Transposable Elements
- DNA, Complementary
- Genetic Variation
- Genome, Human
- Humans
- Pan troglodytes
- Transcription, Genetic