Article
Comparative genomic analysis of human and chimpanzee indicates a key role for indels in primate evolution.
Journal of molecular evolution - 1 Nov 2006
Wetterbom Anna, Sevov Marie, Cavelier Lucia, Bergström Tomas F
Abstract excerpt
Sequence comparison of humans and chimpanzees is of interest to understand the mechanisms behind primate evolution. Here we present an independent analysis of human chromosome 21 and the high-quality BAC clone sequences of the homologous chimpanzee chromosome 22. In contrast to previous studies, we have used global alignment methods and Ensembl predictions of protein coding genes (n = 224) for the analysis....
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