Article
Effect of heterogeneity on the chromosome 10 risk in late-onset Alzheimer disease.
Human mutation - 1 Nov 2007
Liang Xueying, Martin Eden R, Schnetz-Boutaud Nathalie, Bartlett Jackie, Anderson Brent, Züchner Stephan, Gwirtsman Harry, Schmechel Don, Carney Regina, Gilbert John R, Pericak-Vance Margaret A, Haines Jonathan L
Abstract excerpt
With the exception of ApoE (APOE), no universally accepted genetic association has been identified with late-onset Alzheimer disease (AD). A broad region of chromosome 10 has engendered continued interest generated from both preliminary genetic linkage and candidate gene studies. To better examine this region, we combined unbiased genetic linkage with candidate gene association studies. We genotyped 36 SNPs...
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