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Article

Disruption of apical-basal polarity of human embryonic stem cells enhances hematoendothelial differentiation.

Stem cells (Dayton, Ohio) - 1 Sept 2007

Krtolica Ana, Genbacev Olga, Escobedo Carmen, Zdravkovic Tamara, Nordstrom Adam, Vabuena Diana, Nath Aneel, Simon Carlos, Mostov Keith, Fisher Susan J

Abstract excerpt

During murine development, the formation of tight junctions and acquisition of polarity are associated with allocation of the blastomeres on the outer surface of the embryo to the trophoblast lineage, whereas the absence of polarization directs cells to the inner cell mass. Here, we report the re...

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Identifiers

PMID: 17569786
DOI: 10.1634/stemcells.2007-0230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17569786-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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