Article
Are men carrying the apolipoprotein epsilon 4- or epsilon 2 allele less fertile than epsilon 3 epsilon 3 genotypes?
Human genetics - 1 Aug 1996
Gerdes L U, Gerdes C, Hansen P S, Klausen I C, Faergeman O
Abstract excerpt
The epsilon 3 allele in the human gene coding for apolipoprotein E (apoE) is the most common worldwide, but epsilon 4 is probably the ancestral allele. Since apoE is involved in many important biological processes, selection forces could have favoured epsilon 3. We hypothesized that apoE genotype...
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