Article
Role of CYP1B1, MYOC, OPTN, and OPTC genes in adult-onset primary open-angle glaucoma: predominance of CYP1B1 mutations in Indian patients.
Molecular vision - 30 Apr 2007
Kumar Arun, Basavaraj Manjunath G, Gupta Santosh K, Qamar Imteyaz, Ali Abdullah Mahmood, Bajaj Vineeta, Ramesh T K, Prakash D Ravi, Shetty Jyoti S, Dorairaj Syril K
Abstract excerpt
PURPOSE: Mutations in the CYP1B1, MYOC, OPTN, and WDR36 genes result in glaucoma. Given its expression in the optic nerve, it is likely a mutation in the OPTC gene is also involved in initiating glaucoma. This study was designed to evaluate the involvement of the CYP1B1, MYOC, OPTN, and OPTC genes in the etiology of adult-onset primary open-angle glaucoma (POAG) found in 251 Indian patients. METHODS: Blood...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.