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CYP1B1 and MYOC mutations in 116 Chinese patients with primary congenital glaucoma.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Oct 2008

Chen Yuhong, Jiang Deke, Yu Long, Katz Bradley, Zhang Kang, Wan Bo, Sun Xinghuai

Abstract excerpt

OBJECTIVES: To clinically characterize 116 Chinese patients with primary congenital glaucoma and to determine the role of CYP1B1 and MYOC mutations in this cohort. METHODS: This study included 116 unrelated patients with primary congenital glaucoma and 120 ethnically matched, unrelated, healthy controls in China. CYP1B1 and MYOC were amplified from genomic DNA, followed by direct DNA sequencing to identify...

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Source

Identifiers

PMID: 18852424
DOI: 10.1001/archopht.126.10.1443

Genes

MYOC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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