Article
Primary role of CYP1B1 in Indian juvenile-onset POAG patients.
Molecular vision - 20 Apr 2006
Acharya Moulinath, Mookherjee Suddhasil, Bhattacharjee Ashima, Bandyopadhyay Arun Kumar, Daulat Thakur Sanjay Kumar, Bhaduri Gautam, Sen Abhijit, Ray Kunal
Abstract excerpt
PURPOSE: CYP1B1, a member of the cytochrome P450 superfamily of enzymes, has been implicated in primary congenital glaucoma (PCG). Recent studies suggest a role of CYP1B1 in primary open-angle glaucoma (POAG) as a modifier locus. The purpose of the study was to further investigate the potential role of CYP1B1 in POAG patients. METHODS: Two hundred unrelated Indian POAG patients and 100 unrelated ethnically...
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