Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glaucoma-associated CYP1B1 mutations share similar haplotype backgrounds in POAG and PACG phenotypes.

Investigative ophthalmology & visual science - 1 Dec 2007

Chakrabarti Subhabrata, Devi Koilkonda R, Komatireddy Sreelatha, Kaur Kiranpreet, Parikh Rajul S, Mandal Anil K, Chandrasekhar Garudadri, Thomas Ravi

Abstract excerpt

PURPOSE: To understand the involvement of the CYP1B1 gene in cases of primary open-angle (POAG) and primary angle-closure (PACG) glaucomas and obtain the haplotype background of these mutations. METHODS: The entire coding region of CYP1B1 was screened by resequencing in 224 unrelated cases of POAG (n = 134) and PACG (n = 90) and 200 ethnically matched normal control subjects from Indian populations. Six...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Aryl Hydrocarbon Hydroxylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1B1

Share to DNA Mutational Analysis

Share to Glaucoma, Angle-Closure

Share to Glaucoma, Open-Angle

Share to Haplotypes

Share to Linkage Disequilibrium

Source

Identifiers

PMID: 18055790
DOI: 10.1167/iovs.07-0629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glaucoma-associated CYP1B1 mutations share similar haplotype backgrounds in POAG and PACG phenotypes.PMID 18055790Read ↗

CYP1B1 mutation profile of Iranian primary congenital glaucoma patients and associated haplotypes.Semantic proximity Read ↗

Mutation spectrum of CYP1B1 in Chinese patients with primary open-angle glaucoma.Semantic proximity Read ↗

Globally, CYP1B1 mutations in primary congenital glaucoma are strongly structured by geographic and haplotype backgrounds.Semantic proximity Read ↗

Mutational spectrum of the CYP1B1 gene in Pakistani patients with primary congenital glaucoma: novel variants and genotype-phenotype correlations.Semantic proximity Read ↗

Identification of novel CYP1B1 gene mutations in patients with primary congenital and primary open-angle glaucoma.Semantic proximity Read ↗

Mutational analysis of CYP1B1 gene in Iranian pedigrees with glaucoma reveals known and novel mutations.Semantic proximity Read ↗

Genetic Epidemiology of Primary Congenital Glaucoma in the 22 Arab Countries: A Systematic Review.Semantic proximity Read ↗

Meta-analysis of CYP1B1 gene mutations in primary congenital glaucoma patients.Semantic proximity Read ↗

Analysis of CYP1B1 Gene Mutations in Patients with Primary Congenital GlaucomaSemantic proximity Read ↗

Polymorphisms in CYP1B1 gene and the risk of suffering Primary Open-Angle Glaucoma: Systematic review and meta-analysis.Semantic proximity Read ↗

Primary role of CYP1B1 in Indian juvenile-onset POAG patients.Semantic proximity Read ↗

Molecular analysis of CYP1B1 in Omani patients with primary congenital glaucoma: a pilot study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.