Article
Mutation spectrum of CYP1B1 and MYOC genes in Korean patients with primary congenital glaucoma.
Molecular vision - 1 Jan 2011
Kim Hee-Jung, Suh Wool, Park Sung Chul, Kim Chan Yun, Park Ki Ho, Kook Michael S, Kim Yong Yeon, Kim Chang-Sik, Park Chan Kee, Ki Chang-Seok, Kee Changwon
Abstract excerpt
PURPOSE: To elucidate the incidence of cytochrome P450 1B1 (CYP1B1) and myocillin (MYOC) mutations in Korean patients with primary congenital glaucoma (PCG). METHODS: Genomic DNA was collected from peripheral blood of 85 unrelated Korean patients who were diagnosed as having PCG by standard ophthalmological examinations and screened for mutations in the CYP1B1 and MYOC genes by using bi-directional sequencing....
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