Article
Insights into the role of heritable genetic variation in the pharmacokinetics and pharmacodynamics of anticancer drugs.
Expert opinion on pharmacotherapy - 1 Jun 2007
Pander J, Gelderblom H, Guchelaar H J
Abstract excerpt
Pharmacogenetics in oncology will ideally allow oncologists to individualise therapy based on a genetic test result. Severe toxicity and clinically significant underdosing may be avoided, whereas predicted non-responders can be offered alternative therapy. This manuscript gives an overview of her...
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