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Article

Pharmacogenomic discovery approaches: will the real genes please stand up?

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Oct 2005

Walgren Richard A, Meucci Melissa A, McLeod Howard L

Abstract excerpt

Genetic inheritance plays a significant role in the interindividual variability of drug response. The field of pharmacogenomics seeks to identify genetic factors that influence drug response, including both those that are inherited and those that arise within tumors, and use this information to improve drug therapy. Candidate gene approaches have led to clinical tests for toxicity avoidance (eg, TPMT, UGT1A1) and...

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PMID: 16145062
DOI: 10.1200/JCO.2005.03.0825

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TPMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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