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Article

Pharmacogenomics in cancer therapy: is host genome variability important?

Trends in pharmacological sciences - 1 Sept 2004

Petros William P, Evans William E

Abstract excerpt

Pharmacogenomics aims to elucidate the genomic determinants of drug disposition and effect. Because cancer chemotherapy is relatively nonspecific and has narrow therapeutic indices, there is great potential for pharmacogenomics to improve treatment outcomes by either reducing toxicity or increasing efficacy. The diversity of therapeutic targets for anticancer drugs and the intensity of clinical pharmacology...

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PMID: 15559247
DOI: 10.1016/j.tips.2004.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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