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Article

Tyrosine phosphorylation of beta2-chimaerin by Src-family kinase negatively regulates its Rac-specific GAP activity.

Biochimica et biophysica acta - 1 Sept 2007

Kai Masahiro, Yasuda Satoshi, Imai Shin-Ichi, Kanoh Hideo, Sakane Fumio

Abstract excerpt

beta2-Chimaerin, an intracellular receptor for the second messenger diacylglycerol and phorbol esters, is a GTPase-activating protein (GAP) specific for Rac. beta2-Chimaerin negatively controls many Rac-dependent pathophysiological events including tumor development. However, the regulatory mecha...

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Source

Identifiers

PMID: 17560670
DOI: 10.1016/j.bbamcr.2007.05.004

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17560670-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Tyrosine phosphorylation of beta2-chimaerin by Src-family kinase negatively regulates its Rac-specific GAP activity.PMID 17560670Read ↗

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