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Article

Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling.

Cellular signalling - 1 Apr 2008

Caloca María José, Delgado Pilar, Alarcón Balbino, Bustelo Xosé R

Abstract excerpt

Chimaerins are GTPase-activating proteins that inactivate the GTP-hydrolase Rac1 in a diacylglycerol-dependent manner. To date, the study of chimaerins has been done mostly in neuronal cells. Here, we show that alpha2- and beta2-chimaerin are expressed at different levels in T-cells and that they...

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Identifiers

PMID: 18249095
DOI: 10.1016/j.cellsig.2007.12.015
PMCID: PMC2277368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18249095-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling.PMID 18249095Read ↗

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