Protein-protein interactions and disease: use of S. cerevisiae as a model system.

Abstract excerpt

Disease-causing mutations are increasingly being studied to see if they cause the loss or gain of protein-protein interactions. Because the interaction network of humans is poorly understood and difficult to investigate, here we propose the use of Saccharomyces cerevisiae as a model system for understanding the impact of disease-causing mutations on protein-protein interactions. Alignments of human...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Databases, Protein
• Share to Fungal Proteins
• Share to Genetic Diseases, Inborn