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Article

Modeling and analyzing three-dimensional structures of human disease proteins.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2006

Ye Yuzhen, Li Zhanwen, Godzik Adam

Abstract excerpt

Three-dimensional structures of proteins, experimental or predicted, show us how these molecular machines actually work. With the help of information on disease-related mutations, they can also show us how they malfunction in diseases. Such understanding, currently lacking for most human diseases, is an important first step before designing drugs or therapies to cure specific diseases. Here we used homology...

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PMID: 17094259

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