Article
Analysis of CCR5, CCR2, SDF1 and RANTES gene polymorphisms in subjects with HIV-related PML and not determined leukoencephalopathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jan 2008
Guerini Franca R, Delbue Serena, Zanzottera Milena, Agliardi Cristina, Saresella Marina, Mancuso Roberta, Maserati Renato, Marchioni Enrico, Gori Andrea, Ferrante Pasquale
Abstract excerpt
Progressive Multifocal Leukoencephalopathy (PML) is a fatal demyelinating disease of the central nervous system (CNS) caused by JC virus (JCV), a human polyomavirus that can lytically infect and destroy the oligodendrocites in immunosuppressed individuals. After the introduction of highly active antiretroviral therapy (HAART) for AIDS treatment, a PML-like leukoencephalopathy, known as non-determined...
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