Article
Macrophage migration inhibitory factor gene influences the risk of developing tuberculosis in northwestern Colombian population.
Tissue antigens - 1 Jul 2007
Gómez L M, Sánchez E, Ruiz-Narvaez E A, López-Nevot M A, Anaya J-M, Martín J
Abstract excerpt
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that regulates innate and adaptative immunity responses against pathogens. The MIF gene, at 22q11.2, is polymorphic. Functional promoter variants in the MIF gene influence susceptibility to inflammatory diseases in Caucasians and Africans. An association study was carried out to examine the influence of MIF-173 single nucleotide polymorphism...
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