Single nucleotide polymorphisms in cytokine MIF gene promoter region are closely associated with human susceptibility to tuberculosis in a southwestern province of China.

doi:10.1016/j.meegid.2015.12.003

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Article

Single nucleotide polymorphisms in cytokine MIF gene promoter region are closely associated with human susceptibility to tuberculosis in a southwestern province of China.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2016

Liu Aihua, Li Jing, Bao Fukai, Zhu Ziwei, Feng Shi, Yang Jiaru, Wang Lin, Shi Mei, Wen Xia, Zhao Hua, Voravuthikunchai Supayang P

Abstract excerpt

The gene encoding macrophage migration inhibitory factor (MIF) has been proposed as candidate tuberculosis (TB) susceptibility gene. In order to elucidate whether MIF gene variants are associated with susceptibility to retreatment cases of TB, and prevent drug-resistant TB prevalence, we conducted a study based on paired human population data. MIF -173 G/C single nucleotide polymorphisms (rs755622) were genotyped...

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PMID: 26656832
DOI: 10.1016/j.meegid.2015.12.003

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