Article
Osteoblast differentiation is enhanced in rotary cell culture simulated microgravity environments.
Journal of prosthodontics : official journal of the American College of Prosthodontists - 1 Jan 2000
Ko Y Joon, Zaharias Rebecca S, Seabold Denise A, Lafoon John, Schneider Galen B
Abstract excerpt
PURPOSE: As the aging population increases, more people will become reliant on regenerative dental medicine for implant therapy. The objective of this study was to test the hypothesis that 3D rotary cell culture (RCC) environments created by simulated microgravity would enhance osteogenic gene expression using integrin mediated pathways. MATERIALS AND METHODS: Human embryonic palatal mesenchymal (HEPM, ATCC 1486)...
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