Article
A study into the genetic basis of aspirin resistance in Pakistani patients with coronary artery disease.
Pakistan journal of pharmaceutical sciences - 1 Jul 2016
Mukarram Osama, Akhtar Naveed, Junaid Ayesha, Mohyuddin Aisha
Abstract excerpt
Aspirin is a key player in the management and prevention of stroke and myocardial infarction in patients with atherothrombosis. About 12% of Pakistanis suffering from coronary artery disease are resistant to aspirin's effects. Clinical, biochemical and genetic factors are known to be responsible for this phenomenon. We conducted this study to investigate whether previously studied polymorphisms in COX-1, GPIIIa,...
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