Article
Quorum sensing has an unexpected role in virulence in the model pathogen Citrobacter rodentium.
EMBO reports - 1 Jul 2007
Coulthurst Sarah J, Clare Simon, Evans Terry J, Foulds Ian J, Roberts Kevin J, Welch Martin, Dougan Gordon, Salmond George P C
Abstract excerpt
The bacterial mouse pathogen Citrobacter rodentium causes attaching and effacing (AE) lesions in the same manner as pathogenic Escherichia coli, and is an important model for this mode of pathogenesis. Quorum sensing (QS) involves chemical signalling by bacteria to regulate gene expression in response to cell density. E. coli has never been reported to have N-acylhomoserine lactone (AHL) QS, but it does utilize...
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