Article
Investigation of Host and Pathogen Contributions to Infectious Colitis Using the Citrobacter rodentium Mouse Model of Infection.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Bosman Else S, Chan Justin M, Bhullar Kirandeep, Vallance Bruce A
Abstract excerpt
Citrobacter rodentium is used as a model organism to study enteric bacterial infections in mice. Infection occurs via the oral-fecal route and results in the pathogen forming attaching and effacing lesions on infected epithelial cells. Moreover, infection leads to a subsequent host-mediated form of colitis. C. rodentium infection is thus an excellent model to study infectious colitis in vivo, while the ability to...
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