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Article

The CepIR quorum-sensing system contributes to the virulence of Burkholderia cenocepacia respiratory infections.

Microbiology (Reading, England) - 1 Dec 2003

Sokol P A, Sajjan U, Visser M B, Gingues S, Forstner J, Kooi C

Abstract excerpt

The cepIR genes encode an N-acyl homoserine lactone (AHL)-dependent quorum-sensing system consisting of an AHL synthase that directs the synthesis of N-octanoyl-L-homoserine lactone (ohl) and n-hexanoyl-L-homoserine lactone and a transcriptional regulator. The virulence of cepIR mutants was examined in two animal models. Rats were infected with agar beads containing Burkholderia cenocepacia K56-2, K56-I2 (cepI :...

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Identifiers

PMID: 14663096
DOI: 10.1099/mic.0.26540-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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