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Essential Role of the Type III Secretion System Effector NleB in Colonization of Mice by <i>Citrobacter rodentium</i>

21 Mar 2006

Abstract excerpt

Attaching and effacing (A/E) pathogens are a significant cause of gastrointestinal illness in humans and animals. All A/E pathogens carry a large pathogenicity island, termed the locus for enterocyte effacement (LEE), which encodes a type III secretion system that translocates several effector proteins into host cells. To identify novel virulence determinants in A/E pathogens, we performed a signature-tagged...

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PMID: 16552063
DOI: 10.1128/iai.74.4.2328-2337.2006

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