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Human Mesenchymal Stem Cell Microvesicles for Treatment of <i>Escherichia coli</i> Endotoxin-Induced Acute Lung Injury in Mice

13 Aug 2013

Abstract excerpt

We previously found that human mesenchymal stem cells (MSC) or its conditioned medium restored lung protein permeability and reduced alveolar inflammation following Escherichia coli endotoxin-induced acute lung injury (ALI) in an ex vivo perfused human lung in part through the secretion of soluble factors such as keratinocyte growth factor (KGF). Recently, MSC were found to release microvesicles (MVs) that were...

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PMID: 23939814
DOI: 10.1002/stem.1504

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