Article
Rudiment incisors survive and erupt as supernumerary teeth as a result of USAG-1 abrogation.
Biochemical and biophysical research communications - 3 Aug 2007
Murashima-Suginami Akiko, Takahashi Katsu, Kawabata Tomohiro, Sakata Tomoko, Tsukamoto Hiroko, Sugai Manabu, Yanagita Motoko, Shimizu Akira, Sakurai Takeshi, Slavkin Harold C, Bessho Kazuhisa
Abstract excerpt
The term "supernumerary teeth" describes production of more than the normal number of teeth in the primary or permanent dentitions. Their aetiology is not understood. Uterine sensitization associated gene-1 (USAG-1) is a BMP antagonist that plays important roles in the local regulation of BMP signaling by binding and neutralizing BMP activities, and also serves as a modulator of Wnt signaling. We report here that...
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