Article
Insilco analysis of an interaction between an endogenous peptide fragment of NUR77 receptor from human cells and USAG1 protein - may induce teeth regeneration
2024-04-01
Abstract excerpt
BMP-7 and WNT signaling are responsible for the development of teeth. USAG-1 (uterine sensitization associated gene-1) inhibits bone morphogenetic protein-7 protein (BMP-7) as well as WNT receptors leading to suppression of tooth development and growth. The inhibition of USAG-1 using an antibody has been shown to induce tooth regeneration in mice. Hence, USAG-1 is a drug target that is promising enough for teeth g...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 569b3395-1b01-5dc6-b1e7-f0aef2b5e520
- DOI
- 10.21203/rs.3.rs-4193367/v1
