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Insilco analysis of an interaction between an endogenous peptide fragment of NUR77 receptor from human cells and USAG1 protein - may induce teeth regeneration

2024-04-01

Abstract excerpt

BMP-7 and WNT signaling are responsible for the development of teeth. USAG-1 (uterine sensitization associated gene-1) inhibits bone morphogenetic protein-7 protein (BMP-7) as well as WNT receptors leading to suppression of tooth development and growth. The inhibition of USAG-1 using an antibody has been shown to induce tooth regeneration in mice. Hence, USAG-1 is a drug target that is promising enough for teeth g...

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Identifiers and source

Literature Corpus work
569b3395-1b01-5dc6-b1e7-f0aef2b5e520
DOI
10.21203/rs.3.rs-4193367/v1
Open publication

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