Article
Effects of Usag-1 and Bmp7 deficiencies on murine tooth morphogenesis.
BMC developmental biology - 13 May 2016
Saito Kazuyuki, Takahashi Katsu, Asahara Masakazu, Kiso Honoka, Togo Yumiko, Tsukamoto Hiroko, Huang Boyen, Sugai Manabu, Shimizu Akira, Motokawa Masaharu, Slavkin Harold C, Bessho Kazuhisa
Abstract excerpt
BACKGROUND: Wnt5a and Mrfzb1 genes are involved in the regulation of tooth size, and their expression levels are similar to that of Bmp7 during morphogenesis, including during the cap and early bell stages of tooth formation. We previously reported that Usag-1-deficient mice form supernumerary maxillary incisors. Thus, we hypothesized that BMP7 and USAG-1 signaling molecules may play important roles in tooth...
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