Article
PrPCWD in rectal lymphoid tissue of deer (Odocoileus spp.).
The Journal of general virology - 1 Jul 2007
Wolfe Lisa L, Spraker Terry R, González Lorenzo, Dagleish Mark P, Sirochman Tracey M, Brown Jeremy C, Jeffrey Martin, Miller Michael W
Abstract excerpt
The utility of rectal lymphoid tissue sampling for the diagnosis of chronic wasting disease (CWD) infections in mule deer (Odocoileus hemionus) and white-tailed deer (Odocoileus virginianus) was evaluated. CWD-associated prion protein (PrP(CWD)) deposits were observed in the rectal mucosa from 19 orally inoculated mule deer by 381 days post-inoculation (p.i.); similarly, 45 out of 50 naturally infected mule deer...
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