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Article

Minority-variant pfcrt K76T mutations and chloroquine resistance, Malawi.

Emerging infectious diseases - 1 Jun 2007

Juliano Jonathan J, Kwiek Jesse J, Cappell Kathryn, Mwapasa Victor, Meshnick Steven R

Abstract excerpt

Genotyping of the chloroquine-resistance biomarker pfcrt (Plasmodium falciparum chloroquine resistance transporter gene) suggests that, in the absence of chloroquine pressure, Plasmodium falciparum parasites in Malawi have reverted to chloroquine sensitivity. However, malaria infections in Africa are commonly polyclonal, and standard PCRs cannot detect minority genotypes if present in <20% of the parasites in an...

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Identifiers

PMID: 17553226
DOI: 10.3201/eid1306.061182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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