Article
Prevalence of the K76T mutation in the putative Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene and its relation to chloroquine resistance in Mozambique.
The Journal of infectious diseases - 1 May 2001
Mayor A G, Gómez-Olivé X, Aponte J J, Casimiro S, Mabunda S, Dgedge M, Barreto A, Alonso P L
Abstract excerpt
K76T, a mutation in the Plasmodium falciparum chloroquine (CQ) resistance transporter protein, has been implicated in resistance to CQ. A modified 14-day in vivo test to estimate the CQ resistance level was done in southern Mozambique: 21 (42%) of 50 subjects who completed the follow-up were CQ susceptible. Use of msa2-restriction fragment length polymorphism (RFLP) genotyping to differentiate new from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.