Article
Replacement of the essential Dictyostelium Arp2 gene by its Entamoeba homologue using parasexual genetics.
BMC genetics - 6 Jun 2007
Zaki Mehreen, King Jason, Fütterer Klaus, Insall Robert H
Abstract excerpt
BACKGROUND: Cell motility is an essential feature of the pathogenesis and morbidity of amoebiasis caused by Entamoeba histolytica. As motility depends on cytoskeletal organisation and regulation, a study of the molecular components involved is key to a better understanding of amoebic pathogenesis. However, little is known about the physiological roles, interactions and regulation of the proteins of the Entamoeba...
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