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Article

Analysis of integrin alpha7 mutations in prostate cancer, liver cancer, glioblastoma multiforme, and leiomyosarcoma.

Journal of the National Cancer Institute - 6 Jun 2007

Ren Baoguo, Yu Yan P, Tseng George C, Wu Chuanyue, Chen Ka, Rao Uma N, Nelson Joel, Michalopoulos George K, Luo Jian-Hua

Abstract excerpt

BACKGROUND: Integrins are the major adhesive molecules in mammalian cells. Each integrin subtype plays a unique role in cell differentiation and embryo development. However, integrin involvement in carcinogenesis has not been well defined. METHODS: We identified mutations in integrin alpha7 by sequencing genomic DNAs and cDNAs from 122 specimens, including 62 primary human tumor samples, four cell lines, and 56...

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Identifiers

PMID: 17551147
DOI: 10.1093/jnci/djk199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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