Article

Transgenic construction and functional miRNA analysis identify the role of miR-7 in prostate cancer suppression

2022-07-01

Abstract excerpt

<title>Abstract</title> <p>Although miR-7 suppresses the initiation and metastasis in cancers, including prostate cancer (PCa), little is known about its efficacy in the treatment of malignancy in vivo, especially in transgenic mouse models. Herein, to demonstrate the safety of in vivo miR-7 gene editing and its suppressive efficacy on p53-negative tumors, for the first time, a miR-7+ transgenic mouse model was c...

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Literature Corpus work: 430b93a9-ab86-5cde-8a98-8a69530c8312
DOI: 10.21203/rs.3.rs-1770961/v1

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