Article
Transfer of in vitro expanded T lymphocytes after activation with dendritomas prolonged survival of mice challenged with EL4 tumor cells.
International journal of oncology - 1 Jul 2007
Li Jinhua, Theofanous Leigh, Stickel Sara, Bouton-Verville Hilary, Burgin Kelly E, Jakubchak Susan, Wagner Thomas E, Wei Yanzhang
Abstract excerpt
Adoptive T cell transfer after in vitro expansion represents an attractive cancer immunotherapy. The majority of studies so far have been focusing on the expansion of tumor infiltrated lymphocytes (TIL) and some have shown very encouraging results. Recently, we have developed a unique tumor immune response activator, dendritomas, by fusion of dendritic cells and tumor cells. Animal studies and early clinical...
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