Article
Association between the estrogen receptor alpha A908G mutation and outcomes in invasive breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2007
Herynk Matthew H, Parra Irma, Cui Yukun, Beyer Amanda, Wu Meng-Fen, Hilsenbeck Susan G, Fuqua Suzanne A W
Abstract excerpt
PURPOSE: Estrogen receptor alpha (ERalpha) predicts the natural history of breast cancer without intervening therapy. Here, we have optimized the detection of a somatic mutation, an A908G transition of ERalpha, and examined its association with clinical and biological features of invasive breast...
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