Article
[Relationship between radiosensitivity of nasopharyngeal carcinoma and MDR1 gene polymorphism].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 May 2007
Wang Zhi-yuan, Chen Long-hua, Fan Qin, Yan Wei-ping, Chen Yong-qing, Li Qi-sheng, Yuan Ya-wei
Abstract excerpt
OBJECTIVE: To investigate the relationship between human multidrug resistancel gene (MDR1) polymorphisms and the radiosensitivity of nasopharyngeal carcinoma (NPC). METHODS: Blood samples were collected from 59 NPC patients, who were devided into radiosensitive or radioresistant groups according to their responses to radiation therapy. The genotypes for MDR1 polymorphisms (G2677T in exon 21 and C3435T in exon 26)...
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