Article
Polymorphisms in DNA repair genes and MDR1 and the risk for non-Hodgkin lymphoma.
International journal of molecular sciences - 21 Apr 2014
Kim Hee Nam, Kim Nan Young, Yu Li, Kim Yeo-Kyeoung, Lee Il-Kwon, Yang Deok-Hwan, Lee Je-Jung, Shin Min-Ho, Park Kyeong-Soo, Choi Jin-Su, Kim Hyeoung-Joon
Abstract excerpt
The damage caused by oxidative stress and exposure to cigarette smoke and alcohol necessitate DNA damage repair and transport by multidrug resistance-1 (MDR1). To explore the association between polymorphisms in these genes and non-Hodgkin lymphoma risk, we analyzed 15 polymorphisms of 12 genes in a population-based study in Korea (694 cases and 1700 controls). Four genotypes of DNA repair pathway genes (XRCC1...
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