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Article

Sequence specific protein binding to and activation of the TGF-beta 3 promoter through a repeated TCCC motif.

Nucleic acids research - 11 Dec 1991

Lafyatis R, Denhez F, Williams T, Sporn M, Roberts A

Abstract excerpt

We have previously characterized the TGF-beta 3 promoter and shown that the activity of this promoter is highly variable in different cell types. Although the promoter contains a proximal cAMP responsive element, which is critical to basal and forskolin-induced promoter activity, this element is not responsible for the variable, cell-specific regulation of the promoter. In this paper, we identify a 25 base pair...

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Identifiers

PMID: 1754378
DOI: 10.1093/nar/19.23.6419
PMCID: PMC329187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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