Article
Hunchback sequence binding protein suppresses mouse TGF-beta3 promoter in vitro.
Biochemical and biophysical research communications - 4 Aug 2006
Yamazaki Kiyomi, Crowe David L, Shuler Charles F
Abstract excerpt
Transforming growth factor-beta3 (TGF-beta3) has a specific role in vivo in the patterning of embryonic and tissue-specific gene expression. We have cloned and sequenced the mouse TGF-beta3 5'-flanking region to study the transcriptional regulation of this gene. Promoter fragments were cloned into a promoterless luciferase reporter plasmid to study functional activity in a human skin melanoma cell line A375...
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