Hunchback sequence binding protein suppresses mouse TGF-beta3 promoter in vitro.

doi:10.1016/j.bbrc.2006.05.178

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Article

Hunchback sequence binding protein suppresses mouse TGF-beta3 promoter in vitro.

Biochemical and biophysical research communications - 4 Aug 2006

Yamazaki Kiyomi, Crowe David L, Shuler Charles F

Abstract excerpt

Transforming growth factor-beta3 (TGF-beta3) has a specific role in vivo in the patterning of embryonic and tissue-specific gene expression. We have cloned and sequenced the mouse TGF-beta3 5'-flanking region to study the transcriptional regulation of this gene. Promoter fragments were cloned into a promoterless luciferase reporter plasmid to study functional activity in a human skin melanoma cell line A375...

Topics

Animals
Base Sequence
Binding Sites
Carrier Proteins
Cell Line
Conserved Sequence
DNA
Gene Expression Regulation
Genes, Reporter
Genome
Humans
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Promoter Regions, Genetic

Protein Binding

Transforming Growth Factor beta

Transforming Growth Factor beta3

Source

Open in PubMed

Identifiers

PMID: 16781676
DOI: 10.1016/j.bbrc.2006.05.178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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