Article
Regulation of murine TGFbeta2 by Pax3 during early embryonic development.
The Journal of biological chemistry - 25 Aug 2006
Mayanil Chandra S K, Pool Angela, Nakazaki Hiromichi, Reddy Anvesh C, Mania-Farnell Barbara, Yun Beth, George David, McLone David G, Bremer Eric G
Abstract excerpt
Previously our laboratory identified TGFbeta2 as a potential downstream target of Pax3 by utilizing microarray analysis and promoter data base mining (Mayanil, C. S. K., George, D., Freilich, L., Miljan, E. J., Mania-Farnell, B. J., McLone, D. G., and Bremer, E. G. (2001) J. Biol. Chem. 276, 49299-49309). Here we report that Pax3 directly regulates TGFbeta2 transcription by binding to cis-regulatory elements...
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