Article
[PCR determination of an association between class II HLA and pemphigus vulgaris].
Medicina - 1 Jan 1999
Glorio R R, Rodríguez Costa G, Haas R, Larriba J, Fainboim L, Woscoff A
Abstract excerpt
Pemphigus vulgaris (PV) is an autoimmune blistering disease affecting the skin and mucous membranes. It is characterized by the presence of an autoantibody directed against desmoglein 3, which causes acantholysis and blister formation. In this study, we examined the HLA antigens of 30 caucasian argentinian patients compared with 199 controls. We used the PCR-SSO method (Polymerase Chain Reaction-Sequence Specific...
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