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Article

Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence

29 May 2007

Abstract excerpt

BACKGROUND: Potential therapeutic use of mesenchymal stem cells (MSCs) is likely to require large-scale in vitro expansion of the cells before transplantation. MSCs from adipose tissue can be cultured extensively until senescence. However, little is known on the differentiation potential of adipose stem cells (ASCs) upon extended culture and on associated epigenetic alterations. We examined the adipogenic...

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PMID: 17535427
DOI: 10.1186/1471-2121-8-18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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