Article
Donor age negatively impacts adipose tissue-derived mesenchymal stem cell expansion and differentiation.
Journal of translational medicine - 7 Jan 2014
Choudhery Mahmood S, Badowski Michael, Muise Angela, Pierce John, Harris David T
Abstract excerpt
BACKGROUND: Human adipose tissue is an ideal autologous source of mesenchymal stem cells (MSCs) for various regenerative medicine and tissue engineering strategies. Aged patients are one of the primary target populations for many promising applications. It has long been known that advanced age is negatively correlated with an organism's reparative and regenerative potential, but little and conflicting information...
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