Article
Epithelial cell adhesion molecule expression in hepatic stem/progenitor cells is controlled by the molecular clock system.
Biochemical and biophysical research communications - 5 Sept 2018
Kimura Hinako, Matsunaga Naoya, Kakimoto Keisuke, Watanabe Miyako, Tsuruta Akito, Kusunose Naoki, Shiromizu Shoya, Koyanagi Satoru, Ohdo Shigehiro
Abstract excerpt
The circadian rhythm, which regulates various body functions, is transcriptionally controlled by a series of clock gene clusters. The clock genes are related to the pathology of various kinds of diseases. Although there is evidence of serious sleep disorders in patients with chronic hepatitis, the liver regeneration mechanism under chronic hepatitis conditions and its association with the clock genes are not...
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